Novel Approach for Designing Supportive Care in Genetic Disorders of Gastrointestinal Tract: Three-Dimensional Polymer Model of Nutritional Therapies in Cystic Fibrosis, Ulcerative Colitis, and Crohn`s Disease

Paul Zarogoulidis, Ioannis

Abstract

Background: Inflammatory diseases such as; crohn`s disease and ulcerative colitis are responsible for the malnutrition of the patients. These patients due to structural damage within the gastrointestinal tract do not absorb nutrients. Cystic fibrosis is a hereditary disease where the viscosity of mucus induces organ deficiency and nutrition malnutrition. Materials and Methods: A novel polymer tube was constructed in order to evaluate the rheology of different types of nutrients. Results: The current 3D model simulates both light and severe disease with the different types of “traps” that have been constructed within it. Conclusion: Modification of the different nutrients will elicit the proper future modifications that the industry should make for the patients with these underlying diseases.