Omeprazole Induced Acute Interstitial Nephritis in an Adolescent

Damien Noone *,Chia Wei Teoh ,

Abstract

Proton pump inhibitors (PPIs) have emerged as a common cause of drug induced acute interstitial nephritis (AIN) in adults. We present a 15-year-old girl with severe acute kidney injury and biopsy proven AIN attributable to omeprazole. Withdrawal of the drug and steroid therapy affected a recovery of renal function. As the use of PPIs increases in paediatrics, it is important to be aware of this rare but serious side effect.

Relevant Publications in Journal of Nephrology & Therapeutics