One pot synthesis of 2-amino-4-(substituted-phenyl)-6-naphtho[2,1-b]furan-2- yl-nicotinonitrile derivatives by using bismuth nitrate pentahydrate as efficient catalyst

Chandrashekhar C. H., Latha K.

Abstract

A series of 2-amino-4-(substituted-phenyl)-6-naphtho[2,1-b]furan-2-yl-nicotinonitrile derivatives have been prepared by one-pot condensation from malononitrile, aromatic aldehyde, methyl ketone and ammonium acetate by using Bismuth nitrate Pentahydrate as the efficient catalyst. This method has the advantage of short routine, high yields and being environmentally-friendly.