One-pot three-component synthesis of a-amino nitriles catalyzed by Molybdate Sulfuric Acid (MSA)

Hassan Ghasemnejad-Bosra, Reza

Abstract

The molybdate sulfuric acid (MSA) was found to efficiently catalyze for the synthesis of á-amino nitriles from aldehydes, amines and trimethylsilyl cyanide under a solvent-free condition in high yield with short reaction times.