Overlap Syndrome (Systemic Sclerosis and Rheumatoid Arthritis) with Achalasia: An Unusual Association

Daniel Ruiz-Romero, Alicia Sof

Abstract

Both patients with achalasia and systemic sclerosis can complain of esophageal dysphagia. Esophageal manometer remains the most accurate method to evaluate esophageal dismotility. The association of achalasia and systemic sclerosis as an overlap syndrome has not been described yet. This entity could be possibly based on common autoimmune mechanisms and an analogous pathogenesis explained mainly by viral association.

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