Sandeep V.Shinde, Wamanrao N.J
Abstract
The oxidation of 1,4-dihydropyridines (DHPs) to the corresponding pyridine derivatives constitutes the principle metabolic route in biological systems, as well as a facile access to the corresponding pyridine derivatives. Herein, we report a new method for the oxidative aromatization of 1,4-DHPs using the combination of NaBrO3 and NaHSO3. Again the in situ generated HOBr fromthe reaction of NaBrO3 and NaHSO3 is expected to induce the dehydrogenation of 1,4-DHPs.