Reduction of acetophenone derivatives by Spirulina platensis and Nostoc minutum

Takamitsu Utsukihara, Masahiro

Abstract

The reduction of acetophenone derivatives using Spirulina platensis and Nostoc minutum was investigated. It was found that acetophenone derivatives 1a-1o were reduced with good enantioselectivity. The reduction followed PrelogÂ’s rule, giving the (S)-alcohols in all cases.