Relapsing Polychondritis Following Primary Sclerosing Cholangitis: A Rare Coincidence or an Intrinsic Risk?

Hua Li, Bin Liu, Wen Zhang,

Abstract

Primary Sclerosing Cholangitis (PSC) is a rare chronic cholestatic liver disease characterized by inflammation and fibrosis of the bile ducts, resulting in end-stage liver disease. It may coexist with other autoimmune diseases.Relapsing Polychondritis (RP) is an uncommon and severe disease which may lead to destruction of elastic cartilages. A case of RP associated with PSC is presented. Although the occurrence of these diseases together could be coincidental, an association seems immunologically plausible.