Sjogren s Syndrome Involving the Central Nervous System Lesions as the First Performers: A Case Report and Literature Review

Case Report

Xue-Wu Liu, Shan Qiao, Tao

Abstract

Sjogren’s syndrome is primarily a chronic systemic autoimmune disease that involves many systems. However, Sjogren’s syndrome involving the central nervous system lesions, particularly in the central nervous system symptoms as the first performers is uncommon. In this report, we present a 33-year-old woman having PSs with CNS involvement, whose first symptoms presented progressive weakness on the left leg, 2 years later the left upper limb appeared the same symptoms, being diagnosed with Sjogren’s syndrome. To give methylprednisolone pulse therapy, combined with cyclophosphamide and anetholtrithione treatment, her condition improved. After six months’ following-up, no recurrence.

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