Research Article
Janardan Singh Yadav, Jayanti
Abstract
Benzimidazolyl Chalcones(1) were treated with isonicotinoyl hydrazide (1NH) to afford N1 isonicotinoyl -3-benzimidazolyl -5- aryl -2- pyrazolines(2). Reactions of (1) with ethyl acetoacetate in presence of basic alumina gave 6-Carb-ethoxy-3-benzimidazolyl-5-aryl cyclohexenones(3) which on treatment of hydrazine hydrate gave 6-benzimidazolyl-4-aryl 3-oxo- 2,3,4,5 tetrahydro-1H-indazoles(4). All the transformations were carried out under microwave assisted condition. The synthesized compounds were screened for their antimicrobial activity in vitro.