Spectral Characterization and Antibacterial Studies of Arene-Ruthenium (II) Complexes Ligated with Phosphine, Arsine and Heterocyclic Thioamides

R. N. Pandey and K. V. Gautam

Abstract

New cationic half-sandwich organometallic complexes of ruthenium (II) composition [(η6 -pcymene) RuEφ3L]+ BPh4 - (L = Bidentate monoanionic thioamide, E = P/As;) have been synthesized and characterized as their tetraphenylborate salts. All the synthesized ruthenium (II) arene complexes are stable solids and are fully identified by elemental analysis, spectral (IR, UV-vis, 1 H NMR) and conductance data. An octahedral structure of complexes are deduced and thioamide ligand acts as N, S-chelating bidentate. The in vitro antibacterial screening of thioamide ligands and their respective complexes were tested against S. aureus, B. Subtilis and E. coli. The coordination of thioamide ligands to ruthenium (II) exhibited enhance activity.