Research Article
Arumugam Murugesh, Sangeetha S
Abstract
Novel pyrimido[5,4-c]quinolin-2,5-dione (5a-f) were obtained from the precursor 2, 4-dichloro-3-formylquinolines (2a-f) which in turn were synthesized by using Vilsmeir adduct with 4-hydroxyquinolin-2(1H)-ones (1a-f) [18]. Most of the compounds were screened for in vitro growth inhibitory activity against Escherichia coli, Shigella dysenteriae and Klebsiella pneumoniae