Synthesis and Antimicrobial Activities of Some N-Alkoxy α, β- Unsaturated Oxime Ethers

Dimas Kubmarawa, Jeremy T Barm

Abstract

The synthesis, spectral characterization and microbial activity evaluation of a series of some Nalkoxy (and acyloxy) α, β-unsaturated oxime ethers were carried out. The products obtained were characterized and tested for bioactivity against Stapphylococcus aurreus, Escherichia coli, Candidas albicans and Sacharomyces cereviciae. Alkyl halides and a group of compounds comprising of acyl chlorides derived from fatty acids of palm oil (palmitic acid, oleic acid) were coupled with cinnamaldoxime and crotonaldoxime to form the ethers or esters.