Synthesis and Antimicrobial Activity of New Condensed Coumarin 4-Acetohydrazide

Kailash Pancholia, Mahendra Bo

Abstract

Synthesis of a series of 4-(2-(2-(substitutedbenzylidene)hydrazinyl)-2-oxoethyl)-2-oxo-2H-chromen-7-yl acetate. (3a-l) was achieved from different substituted 2-(7-Hydroxy-2-oxo-2H-chromen-4-yl) acetohydrazide, acetic anhydride and using few drops H2SO4 added and string with DCM. The structures of the products were supported by FTIR, PMR and mass spectral data.