Synthesis and antioxidant activity of disubstituted 1,3,4-oxadiazoles, 1,3,4- thiadiazoles and 1,2,4-triazoles

A. Padmaja,C. Rajasekhar,A. Mu

Abstract

Some new disubstituted 1,3,4-oxadiazoles / thiadiazoles and 1,2,4-triazoles were synthesized by cyclocondensation of arylsulfonylethylsulfonylacetic acid methyl ester and benzylsulfonylethylsulfonylacetic acid methyl ester with different nucleophiles. All the new compounds were evaluated for antioxidant activity. The compound 8c exhibited greater antioxidant activity.