Synthesis and biological evaluation of carbamate and sulfonamide derivatives of carvedilol

Research Article

Sana Venkata Lakshmi Reddya, S

Abstract

The modified structures of Carvedilol as their carbamates and sulfonamides were synthesized by the reaction of Cavedilol with different Chloroformates/sulfonylchlorides in the presence of triethylamine at reflux temperature in THF. The newly synthesized compounds were characterized by IR, NMR (1H & 13C), LCMS and C, H, N elemental analysis. All the title compounds were screened for their antimicrobial activity.

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