Synthesis and Characterization of some biologically active 2, 5-Substituted Oxadiazoles

Wanale S. G.*, Pachling S. P.

Abstract

Present paper reports the synthesis of four new biologically active 2, 5-substituted oxadiazoles by oxidative cyclization of the semicarbazones obtained from the reaction of semicarbazides with corresponding aromatic aldehydes. The structures of target oxadiazoles were confirmed by elemental, IR, NMR and LCMS data. These compounds were screened for their antifungal activity and found active.