Synthesis and characterization of the new type of tetrazoles containing barbiturates.

Mahdokht Rezazadeh, Amin Azimi

Abstract

Reaction of 4-cyano benzaldehyde with sodiumazide in presence of ammoniumChloride in dimethyl formamide under reflux conditions gave 4-(1Htetrazole- 5-yl)benzaldehyde, which was condense with barbiturates under knoevenagel condensations to give newsubstituted derivatives of tetrazoles with good yield.