Hemlata Kaur, Sunil Kumar, K.K
Abstract
A series of 2-(Heterocyclic-amino/hydrazino-methylene)-1, 5-benzothia/ oxazepine-4 (5H) ones (1-26) have been synthesized by the reaction of 2- bromomethyl-1, 5-benzo-thia/oxazepine 4(5H) oneswith various substituted heterocyclic amines or hydrazines. All the newly synthesized compounds were screened for their antipsychotic and anticonvulsant activities at the dose of 40mg/kg i.p. and were compared with standard drugs. Compound 19 was the most potent compound of this series. Structure of all the synthesized compidated by elemental (C, H, N) and spectral (IR, and 1H-NMR) analysis.