Synthesis and pharmacological evaluation of some substituted imidazoles

D. D. Bhragual*1 , N. Kumar1

Abstract

Titled compounds N-1-phenyl 3- substituted phenyl indolo (2, 3) imidazole was prepared by condensing different aryl aldehydes with N-1-phenyl isatin in presence of ammonium acetate and glacial acetic acid. N-1-phenyl isatin was prepared by reaction of isatin with chloro benzene in presence of tetrahydrofuran and triethyl amine. Synthesized compounds were checked for there anticonvulsant activity.