Synthesis and spectral characterization of related compounds of Losartan potassium, an anti-hypertensive drug substance

D.P.Lokamaheshwari, G.Naveeenc

Abstract

Losartan potassium (1) is a known anti-hypertensive drug substance, recently appeared in the European pharmacopoeia with the several process related compounds/impurities. Out of (12) related compounds (6) were synthesized and characterized based on IR, NMR and MS spectral data, and same thing was described in this article.

Relevant Publications in Organic Chemistry : An Indian Journal