Synthesis of 2-p-Nitrobenzyl-5-Phenyl-1, 3, 4-Oxadiazole Using Green Solvent

Prakash Kumar, Arbind Kumar an

Abstract

p-nitro-phenylacetic acid hydrazide was reacted with benzoyl chloride to produce diacyl hydrazide and simultaneously subjected to cyclization to 2,5-disubstituted oxadiazole using dichloromethane in place of earlier used carbon tetrachloride.