Synthesis of 2-(Substituted benzylsulfanyl)-4,5-dihydrothiazoles

D.Shobha, M.Adharvana Chari, R

Abstract

A simple and convenient procedure for the preparation of 2-(substituted benzylsulfanyl)-4,5-dihydrothiazoles by the reaction of 4,5-dihydro-thiazole- 2-thiol and benzyl bromides in methanol/Na2CO3 condition has been reported. This new method consistently has the advantage of excellent yields (84-93%) and short reaction time (3 h) at reflux temperature.

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