M.Suresh, P.Lavanya, K.Vasu, C
Abstract
Selective preparation of 6-chloro-8-subtituted-9[H]-purines has been achieved, by treating 6-halo-4,5-diaminopyrimidine and substituted aromatic acid with pyridine reagent to get 75–90% yields by refluxing at short reaction time 1.5 to 2.0 hours. Their chemical structures were characterized using IR, H1 NMR and Mass spectral studies. All the above compounds were screened for anti-microbial activity, anti-oxidant activity and their bioassay showed them to possess significant antimicrobial activity and antioxidant activity.