Research Article
Gao Xiu-mei Han Wei-Dong Yu
Abstract
The acute toxicity and mutagenesis of water extract from Avicennia marina fruits in mice were studied with the oral acute toxicity test according to Karber’s method and the bone-marrow micronucleus test for mutagenic observation.The results showed the water extract from A. marina fruits presented theacute per oral toxicity at LD50 >10.000 mg/kg; the bone-marrow nicrobucleus test indicated no mutagenic effects. Water extract from A.Marina fruits belong to non toxic compounds and has no mutagenic effects under the experimental conditions.