The Association between Maternal Vitamin D Status in Gestation and Pre-Eclampsia

Arsala L, Silva Costa FD and M

Abstract

Preeclampsia is a complex and life threatening pregnancy disorder is mojor cause of maternal and neonatal morbidity and mortality. A growing body of evidence has demonstrated that low vitamin D is associated with the pathophysiology of preeclampsia. As such, identification of the mechanisms behind this relationship and placental vascular endothelial dysfunction presents itself as a significant modifiable disease risk factor, which if identified and managed appropriately, may make a significant impact in reducing the burden of disease.