Review Article
Roger Gregory Biringer
Abstract
Eicosanoids are amphipathic, bioactive signalling molecules involved in a wide range of biological processes from homeostasis of blood pressure and blood flow to inflammation, pain, cell survival, and the progression of numerous disease states. The purpose of this review is to present an up-to-date and comprehensive overview of the enzymes of the eicosanoid pathway, their substrates, products, structure, isoforms, and regulation.