Research Article
Jules Clement Nguedia Assob, M
Abstract
Uric acid has been associated with hypertension in many studies involving different populations but little or no information was found on this association in a Cameroonian population. The aim of this study therefore was to correlate serum uric acid concentrations with blood pressure measurements in individuals who are hypertensive, pre-hypertensive and normotensive, and to investigate the possibility of existence of an association between uric acid levels and other risk factors for hypertension. A total of 297 adults from Fako Division participated in the study. Blood pressure, serum uric acid, fasting blood glucose (subjects with ≥ 110mg/dl were excluded), lipids, body mass index and waist circumference were measured. Individuals who were pre- hypertensive had the highest mean uric acid concentration which was significantly higher than that for normotensives (P<0.0001). There was a significant positive correlation between uric acid with systolic and diastolic blood pressure (P<0.0001; P<0.0001), respectively. A significant positive correlation was also observed between serum uric acid levels with gender, age, triglycerides and life style patterns (P<0.0001). However, adjusting for these confounders did not change the increasing trend observed between serum uric acid with both systolic and diastolic blood pressure.