Understanding the Mechanism of Antioxidant Potential of Organochalcogens in Rat's Brain Preparation

Research Article

Waseem Hassan, Senthil Narayan

Abstract

In the quest to explore mechanism of action of organochalcogens a series of them are tested for their structuralactivity relationship using rat’s brain preparation. Dichalcogenides are better anti-oxidants than structurally analogues mono- chalcogenides. Effects of electron donating and withdrawing groups have been explored and explained in detail. We have also proved that structural isomerisation does not influence the anti-oxidant activity of these compounds.

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